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Molecular basis of Mediator subunit 12 in the pathogensis of uterine fibroids.

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Molecular basis of Mediator subunit 12 in the pathogensis of uterine fibroids.

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Author	Park, Min ju.
Title	Molecular basis of Mediator subunit 12 in the pathogensis of uterine fibroids.
Subject	Leiomyoma Neoplasms Female Hispanic Americans
Description	Dissertation (Ph.D.).--University of Texas Graduate School of Biomedical Sciences at San Antonio, 2017. The principle objective of this dissertation was therefore two-fold: first, to establish the frequency of Mediator subunit 12 mutations in uterine leiomyomas from Hispanic women of south Texas in an effort to further catalog Mediator subunit 12 driver alterations in diverse ethnic populations and, second, to determine whether and how Mediator subunit 12 or its oncogenic mutant derivatives activate the Cyclin dependent kinase 8 paralog Cyclin dependent kinase 19. -- Abstract
Publisher	San Antonio : University of Texas Health Science Center San Antonio.
Date.Original	2017
Identifier	ETD
Rights	The digital reproductions on this site, held by the Library at the University of Texas Health Science Center at San Antonio (UTHSCSA), including its satellite libraries, are provided to the students, faculty and staff of the UTHSCSA and others who visit this site for research, teaching and learning only. Further distribution and/or any commercial use of the works from this site is strictly forbidden without the permission of the copyright holder.